20©2025 WuXi Biologics. All rights reserved.Driving Low CoGs Through Process IntensificationCoGs ↓TFBTiter ↑DS Amount(Kg/2KL Batch)100%3.0-8.0 g/L5-15 KgWuXi Biologics’Track Record of Intensified ProcessIntensified FB (IFB)Ultra-Intensified FB (UI)Intensified PerfusionCulture (IPC)50-80%15-30%20-50%5.0-12.5 g/L15-50 g/L20-120 g/L7-20 Kg25-85 Kg40-100 KgBLA 9%Late Stage36%Process Lock 9%IND46%Applied in 11 Projects, up to 12000LLPD 75%Applied in 4 Projects (+15 in feasibility stage), up to 2000LIND 25%Applied in 23 Projects,up to 2000LIND 75%Process Lock 26%BLA 17%Late stage 4%↑